This is the first study that conducted to the effect of cold plasma on the healing of gingival wound in diabetic rabbits.
Eighteen healthy rabbits is purched from pastor institute. The aloxan was injected to the rabbits. After induction of anesthesia the gum tissue is removed. The rabbits were treated by the plasma jet for 3, 5 and 10days each day 30s and they were considered histological.
After 3days the plasma jet treatment, the production of collagen and fibroblast and migration of epithelial cells is observed. As can be seen from the results after 5days the cold plasma treatment the increase of neovascularation, collagen and inflammatory infiltration is seen in gum tissue. Formation of granulation tissue is seen after 10days the plasma jet treatment.
The cold plasma treatment is an effective way for gingival wound treatment. Cold plasma treatment resulted in reduction of inflammatory phase and accelerates the recovery phase by increase neovascularation and collagen production.
The cold plasma treatment is an effective way for gingival wound treatment. Cold plasma treatment resulted in reduction of inflammatory phase and accelerates the recovery phase by increase neovascularation and collagen production.Increased serum levels of advanced glycation end products (AGEs), caspase-3 (Cas-3) and matrix metalloproteinase-9 (MMP-9) have been reported in diabetic patients. This study aimed to evaluate association of anthropometric, dietary, and therapeutic factors with serum levels of methylglyoxal (MGO), carboxymethyl lysine (CML), pentosidine (Pen), Cas-3, and MMP-9 in diabetic patients.
The current study included 36 diabetic subjects. Dietary intake of the participants was assessed using three-day 24-h recall survey and anthropometric indices were measured. Demographic factors and medication intake of every subject were obtained. Serum levels of CML, MGO, Pen, MMP-9, and Cas-3 were measured using ELISA method.
Gliclazide consumption was positively correlated with MMP-9 and Cas-3, but not AGEs levels. Females had higher MGO level compared with males. https://www.selleckchem.com/products/PLX-4032.html Further, CML levels were negatively correlated with BMI and WHR. Dietary protein intake was positively correlated with MMP-9, Cas-3, and MGO levels. As well as dietary energy and fat intake had significant positive relationship with serum Cas-3 concentration.
It is concluded that anthropometric characteristics, dietary intake, and therapeutic medications are possible factors that may determine the circulating levels of AGEs, MMP-9, and Cas-3 in patients with diabetes.
It is concluded that anthropometric characteristics, dietary intake, and therapeutic medications are possible factors that may determine the circulating levels of AGEs, MMP-9, and Cas-3 in patients with diabetes.The diabetic nephropathy is associated with oxidative stress and increases in pigment epithelium-derived factor (PEDF) level in the patient's blood. For the first time, authors investigated the effect of methylethylpiridinol addition to the therapy on oxidative status and pigment epithelium-derived factor concentrations, and examined the relationship between these indicators and clinical markers of pathology development.
Study design open label randomized controlled trial study. Authors assessed the effect of methylethylpiridinol addition to the therapy vs basic treatment on antioxidant and NADPH-generating enzymes activity, glutathione's concentration and freeradical-induced oxidation's intensity using a spectrophotometric method and iron-induced biochemiluminescence. The pigment epithelium-derived factor concentration in the serum was measured by enzyme-linked immunosorbent assay.
Patients receiving combination therapy with methylethylpiridinol showed a more substantial increase in activity of glutathstimulating effect on the patients' oxidative status in comparison with standard treatment, and reliably decreased pigment epithelium-derived factor level in patients' serum. The observed differences seem to be associated with the antioxidant activity of methylethylpiridinol which contributing to the mitigation of oxidative stress reducing at diabetes mellitus.This study aimed to investigate the effects of raw red beetroot consumption on metabolic markers and cognitive function in type 2 diabetes patients.
In a quasi-experimental study, 44 type 2 diabetes patients (57?±?4.5years) consumed raw red beetroot (100g, daily), for 8weeks. Metabolic markers including body weight, glucose and lipid profile parameters, inflammatory and oxidative stress markers, paraoxonase-1 activity, hepatic enzymes, blood pressure and cognitive function were measured at the beginning and end of 8weeks.
Raw red beetroot consumption resulted in a significant decrease in fasting blood sugar (FBS) levels (-13.53mg/dL), glycosylated hemoglobin (HbA1c)(-0.34%), apolipoproteinB100 (ApoB100) (-8.25mg/dl), aspartate aminotransferase (AST) (-1.75U/L), alanine aminotransferase (ALT) (-3.7U/L), homocysteine (-7.88μmol/l), systolic (-0.73mmHg) and diastolic blood pressure (-0.34mmHg), anda significant increase in total antioxidant capacity (TAC) (105μmol/L) and cognitive function tests (all values &lt;0.05). Other variables did not change significantly after the intervention.
Raw red beetroot consumption for 8weeks in T2DM patients has beneficial impacts on cognitive function, glucose metabolism and other metabolic markers.
Raw red beetroot consumption for 8 weeks in T2DM patients has beneficial impacts on cognitive function, glucose metabolism and other metabolic markers.Fungal infections including is one of the most important health concerns among type 2 diabetic patients. Therefore, this study aimed to determine the prevalence of skin infection in patients with type 2 diabetes in a systematic review and meta-analysis.
In this review study, data were extracted from national and international databases of SID, MagIran, IranMedex, IranDoc, Google Scholar, Cochrane, Embase, ScienceDirect, Scopus, PubMed, and Web of Science (WoS) with no time limit until January 2021. The random effects model was used for doing analysis and the Iindex was used for assessing the heterogeneity of studies. Data were analyzed using Comprehensive Meta-Analysis (Version 2).
The prevalence of skin infection in patients with type 2 diabetes was 11.4% (95% CI 8.9%-14.4%) in 13 reviewed articles with a sample size of 1348. Regarding the heterogeneity based on meta-regression, there was a significant difference between the effect of sample size (?&lt;?0.05) and the prevalence of skin infection in patients with type 2 diabetes.